Depression is a heavy burden that can affect every aspect of life. In times of despair, turning to Scripture offers comfort, hope, and strength. The Bible is filled with verses that provide reassurance and remind us that we are never alone. Whether you are struggling with depression yourself or seeking to support a loved one, these Bible verses for depression can be a source of encouragement.
50 Powerful Bible Verses for Depression
- Psalm 34:17-18
“The righteous cry out, and the Lord hears them; he delivers them from all their troubles. The Lord is close to the brokenhearted and saves those who are crushed in spirit.”
- Matthew 11:28
“Come to me, all you who are weary and burdened, and I will give you rest.”
- Isaiah 41:10
“So do not fear, for I am with you; do not be dismayed, for I am your God. I will strengthen you and help you; I will uphold you with my righteous right hand.”
- 1 Peter 5:7
“Cast all your anxiety on him because he cares for you.”
- Psalm 40:1-3
“I waited patiently for the Lord; he turned to me and heard my cry. He lifted me out of the slimy pit, out of the mud and mire; he set my feet on a rock and gave me a firm place to stand. He put a new song in my mouth, a hymn of praise to our God.”
- Jeremiah 29:11
“For I know the plans I have for you,” declares the Lord, “plans to prosper you and not to harm you, plans to give you hope and a future.”
- Philippians 4:6-7
“Do not be anxious about anything, but in every situation, by prayer and petition, with thanksgiving, present your requests to God. And the peace of God, which transcends all understanding, will guard your hearts and your minds in Christ Jesus.”
- Psalm 42:11
“Why, my soul, are you downcast? Why so disturbed within me? Put your hope in God, for I will yet praise him, my Savior and my God.”
- John 16:33
“I have told you these things, so that in me you may have peace. In this world you will have trouble. But take heart! I have overcome the world.”
- Romans 8:38-39
“For I am convinced that neither death nor life, neither angels nor demons, neither the present nor the future, nor any powers, neither height nor depth, nor anything else in all creation, will be able to separate us from the love of God that is in Christ Jesus our Lord.”
- Psalm 9:9
“The Lord is a refuge for the oppressed, a stronghold in times of trouble.”
- Lamentations 3:22-23
“Because of the Lord’s great love we are not consumed, for his compassions never fail. They are new every morning; great is your faithfulness.”
- Psalm 3:3
“But you, Lord, are a shield around me, my glory, the One who lifts my head high.”
- Isaiah 40:31
“But those who hope in the Lord will renew their strength. They will soar on wings like eagles; they will run and not grow weary, they will walk and not be faint.”
- Psalm 23:4
“Even though I walk through the darkest valley, I will fear no evil, for you are with me; your rod and your staff, they comfort me.”
- 2 Corinthians 12:9
“But he said to me, ‘My grace is sufficient for you, for my power is made perfect in weakness.’ Therefore I will boast all the more gladly about my weaknesses, so that Christ’s power may rest on me.”
- Psalm 55:22
“Cast your cares on the Lord and he will sustain you; he will never let the righteous be shaken.”
- Hebrews 4:15-16
“For we do not have a high priest who is unable to empathize with our weaknesses, but we have one who has been tempted in every way, just as we are—yet he did not sin. Let us then approach God’s throne of grace with confidence, so that we may receive mercy and find grace to help us in our time of need.”
- Psalm 30:5
“For his anger lasts only a moment, but his favor lasts a lifetime; weeping may stay for the night, but rejoicing comes in the morning.”
- 2 Timothy 1:7
“For the Spirit God gave us does not make us timid, but gives us power, love and self-discipline.”
- Psalm 147:3
“He heals the brokenhearted and binds up their wounds.”
- Romans 15:13
“May the God of hope fill you with all joy and peace as you trust in him, so that you may overflow with hope by the power of the Holy Spirit.”
- Psalm 46:1-2
“God is our refuge and strength, an ever-present help in trouble. Therefore we will not fear, though the earth give way and the mountains fall into the heart of the sea.”
- Philippians 4:13
“I can do all this through him who gives me strength.”
- Psalm 94:19
“When anxiety was great within me, your consolation brought me joy.”
- 1 Thessalonians 5:16-18
“Rejoice always, pray continually, give thanks in all circumstances; for this is God’s will for you in Christ Jesus.”
- Psalm 62:5-6
“Yes, my soul, find rest in God; my hope comes from him. Truly he is my rock and my salvation; he is my fortress, I will not be shaken.”
- Isaiah 43:2
“When you pass through the waters, I will be with you; and when you pass through the rivers, they will not sweep over you. When you walk through the fire, you will not be burned; the flames will not set you ablaze.”
- Psalm 116:1-2
“I love the Lord, for he heard my voice; he heard my cry for mercy. Because he turned his ear to me, I will call on him as long as I live.”
- Romans 8:31
“What, then, shall we say in response to these things? If God is for us, who can be against us?”
- Psalm 143:7-8
“Answer me quickly, Lord; my spirit fails. Do not hide your face from me or I will be like those who go down to the pit. Let the morning bring me word of your unfailing love, for I have put my trust in you. Show me the way I should go, for to you I entrust my life.”
- Proverbs 3:5-6
“Trust in the Lord with all your heart and lean not on your own understanding; in all your ways submit to him, and he will make your paths straight.”
- Psalm 34:4
“I sought the Lord, and he answered me; he delivered me from all my fears.”
- Isaiah 26:3
“You will keep in perfect peace those whose minds are steadfast, because they trust in you.”
- John 14:27
“Peace I leave with you; my peace I give you. I do not give to you as the world gives. Do not let your hearts be troubled and do not be afraid.”
- Psalm 27:1
“The Lord is my light and my salvation—whom shall I fear? The Lord is the stronghold of my life—of whom shall I be afraid?”
- James 1:2-4
“Consider it pure joy, my brothers and sisters, whenever you face trials of many kinds, because you know that the testing of your faith produces perseverance. Let perseverance finish its work so that you may be mature and complete, not lacking anything.”
- Psalm 18:2
“The Lord is my rock, my fortress and my deliverer; my God is my rock, in whom I take refuge, my shield and the horn of my salvation, my stronghold.”
- 2 Corinthians 4:16-18
“Therefore we do not lose heart. Though outwardly we are wasting away, yet inwardly we are being renewed day by day. For our light and momentary troubles are achieving for us an eternal glory that far outweighs them all. So we fix our eyes not on what is seen, but on what is unseen, since what is seen is temporary, but what is unseen is eternal.”
- Psalm 16:8
“I keep my eyes always on the Lord. With him at my right hand, I will not be shaken.”
- Isaiah 35:10
“And those the Lord has rescued will return. They will enter Zion with singing; everlasting joy will crown their heads. Gladness and joy will overtake them, and sorrow and sighing will flee away.”
- Psalm 103:1-4
“Praise the Lord, my soul; all my inmost being, praise his holy name. Praise the Lord, my soul, and forget not all his benefits—who forgives all your sins and heals all your diseases, who redeems your life from the pit and crowns you with love and compassion.”
- Deuteronomy 31:6
“Be strong and courageous. Do not be afraid or terrified because of them, for the Lord your God goes with you; he will never leave you nor forsake you.”
- Psalm 91:1-2
“Whoever dwells in the shelter of the Most High will rest in the shadow of the Almighty. I will say of the Lord, ‘He is my refuge and my fortress, my God, in whom I trust.’”
- Revelation 21:4
“He will wipe every tear from their eyes. There will be no more death or mourning or crying or pain, for the old order of things has passed away.”
- Psalm 118:24
“The Lord has done it this very day; let us rejoice today and be glad.”
- Proverbs 12:25
“Anxiety weighs down the heart, but a kind word cheers it up.”
- Nehemiah 8:10
“Do not grieve, for the joy of the Lord is your strength.”
- Psalm 119:50
“My comfort in my suffering is this: Your promise preserves my life.”
- 2 Corinthians 1:3-4
“Praise be to the God and Father of our Lord Jesus Christ, the Father of compassion and the God of all comfort, who comforts us in all our troubles, so that we can comfort those in any trouble with the comfort we ourselves receive from God.”
Conclusion
His Word is a source of light in the darkness, guiding us through our struggles and lifting our spirits. Whether you are facing depression yourself or supporting someone who is, these verses provide a foundation of faith and trust in God’s unchanging love. Let these scriptures encourage you and remind you that you are never alone in your journey.
